Olink Explore 3072/384 Panels – Ultra-High Multiplex Protein Profiling Platform

Olink Explore 3072 and Explore 384 panels redefine large-scale proteomic research by combining ultra-sensitive PEA technology with next-generation sequencing readout. With the Olink Explore 3072 assay, researchers can measure more than 3,000 proteins across immune, oncology, neurology, and cardiometabolic pathways—all from just 1–3 µL of sample. The modular Olink Explore 384 panels offer targeted coverage of 384 proteins, while the 3072 format integrates eight panels for the broadest possible assay list. Whether you're mapping disease biology, validating biomarkers, or designing translational studies, Olink Explore delivers data quality, scalability, and flexibility.

3,000+ proteins profiled in Olink Explore 3072
384-protein themed panels for focused research needs
PEA technology for ultra-sensitive and reliable detection
Low sample volume and adaptable pricing for every project

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Olink Explore 3072/384 Panels at Creative Proteomics

Explore 3072
Explore 384
Panels & Assays
Workflow
Advantages
Data & QC
Samples
FAQ

What is Olink Explore 3072?

Olink Explore 3072/384 Panels at Creative Proteomics

Olink Explore 3072 is the most comprehensive proteomics solution in the Olink portfolio, offering an unmatched ultra-high multiplex protein profiling capability. This platform combines eight Olink Explore 384 panels to create a single workflow covering 3,000+ protein assays, streamlining everything from biomarker discovery to drug development studies.

Key Advantages of Olink Explore 3072 Technology:

3,000+ proteins measured per run – comprehensive systems-level view
8 panels combined – enabling cross-pathway insights in a single experiment
1–3 µL sample requirement – suitable for rare or precious specimens
Consistent data output – PEA-driven NPX values compatible across batches

Whether you're compiling a complete assay list for large cohort studies or need a scalable proteomics platform for translational research, Olink Explore 3072 assay technology provides a data-rich, high-confidence solution for modern biomedical projects.

What is Olink Explore 384?

Olink Explore 384 panels are the building blocks of the Explore proteomics platform, designed for targeted, high-multiplex protein profiling. Each Explore 384 panel measures 384 carefully selected proteins from as little as 1–3 µL of sample, making it ideal for both focused studies and as part of the Explore 3072 assay combination.

Thematic Panel Design

The 384-panel format is organized into disease- and pathway-focused themes, allowing researchers to choose exactly the coverage they need—or combine multiple panels for broader insights.

Key Features of Olink Explore 384 Panels:

384 proteins per panel – broad, yet targeted coverage
Compatible with serum, plasma, CSF, and other biofluids
Uses the same PEA technology as Explore 3072 for seamless data integration

Olink Explore 3072/384 Assay List

Cardiometabolic

Olink Explore 384 Cardiometabolic Panel

Biomarkers for cardiovascular and metabolic health (lipids, hormones, vascular biology)

Olink Explore 384 Cardiometabolic II Panel

Expanded panel for advanced cardiometabolic pathways and novel markers

Inflammation

Olink Explore 384 Inflammation Panel

Covers cytokines and chemokines for inflammatory response research

Olink Explore 384 Inflammation II Panel

Adds deeper coverage of immune mediators and inflammatory regulators

Neurology

Olink Explore 384 Neurology Panel

Focused on CNS biomarkers and neurodegenerative disease proteins

Olink Explore 384 Neurology II Panel

Expands on neuroinflammation and synaptic signalling proteins

Oncology

Olink Explore 384 Oncology Panel

Tumor biology, cell cycle, and cancer-related protein pathways

Olink Explore 384 Oncology II Panel

Adds broader cancer biomarker coverage and regulatory proteins

Explore 3072/1536 Combinations

Olink Explore 3072 (8 Panel Combinations)

The full Explore platform: eight panels combined, covering 3,072 proteins for the broadest pathway insights.

Olink Explore 1536 (4 Panel Combinations)

Combine four 384 panels for profiling 1,536 proteins in one run—ideal for mid-scale biomarker discovery.

Workflow of Olink Proteomics

Why Choose Olink Explore 3072/384?

Multiplex Power – Measure 3,072 proteins in one workflow with Olink Explore 3072, or focus on 384-protein panels for targeted studies.

Proven Technology – Olink's Proximity Extension Assay (PEA) paired with NGS readout ensures high specificity and ultra-sensitive detection.

Minimal Sample Volume – Requires as little as 1–3 µL per assay, preserving precious or limited specimens.

Consistent Data – All panels produce normalized NPX values, enabling cross-panel comparisons and multi-cohort studies.

Scalable Configurations – Start with one Olink Explore 384 panel, expand to 1536 or the full 3072-panel combination as your research grows.

Cost-Efficient Multiplexing – Analyze hundreds or thousands of proteins in a single run, optimizing cost per sample.

Olink Explore 3072/384 Data Visualization

Comprehensive NPX Data Table – Normalized Protein eXpression (NPX) values for every protein across all samples.
High-Resolution Data Visualizations – Volcano Plot, Heatmap, and Scatter Plot for quick interpretation.
Quality Control (QC) Summary – Internal/external control performance and pass/fail status for each sample.
Assay & Panel Information – List of included Olink Explore 384 panels and combined 3072 assays.
Method Overview – Brief description of PEA technology and NGS-based readout used in the analysis.
Exportable Data Files – Excel/CSV tables and a PDF summary report ready for further research or presentations.

Explore 3072/384 Demo Results – Volcano Plot, Heatmap, and Scatter Plot from Olink Explore panels showing protein regulation, expression clustering, and reproducibility.

Sample Requirements

Sample Type	Minimum Volume per Panel	Matrix / Notes	Storage Conditions
Serum	50 µL	Use clot activator tubes; avoid haemolysis	Store at −80 °C
Plasma	50 µL	EDTA- or heparin plasma preferred	Store at −80 °C
CSF (Cerebrospinal Fluid)	50 µL	Collect under sterile conditions	Store at −80 °C
Cell Culture Supernatant	50–100 µL	Clarify by centrifugation to remove debris	Store at −20 °C to −80 °C
Urine (optional)	100 µL	Collect midstream sample, centrifuge before use	Store at −80 °C
Other Matrices	Case-by-case	Contact us for guidance (e.g., saliva, synovial fluid, tissue homogenates)	Store at −80 °C

Sample Handling Guidelines

Avoid freeze–thaw cycles: More than two freeze–thaw events may affect protein stability.
Labeling: Each tube must be clearly labeled with sample ID, matrix type, and collection date.
Shipping: Send samples on dry ice to maintain cold chain integrity.
Volume buffer: Provide an extra 10–15 µL for QC and repeat testing if needed.

FAQ – Frequently Asked Questions

What is the difference between Olink Explore 384 and Olink Explore 3072?

The Olink Explore 384 panels each measure 384 proteins in a focused biological area. The Olink Explore 3072 assay combines eight Explore 384 panels into one workflow, enabling the analysis of more than 3,000 proteins across multiple pathways.

What technologies power Olink Explore 3072 assays?

All Explore panels use PEA (Proximity Extension Assay) technology with next-generation sequencing (NGS) readout, delivering high sensitivity and specificity even for low-abundance proteins.

How comprehensive is the Olink Explore 3072 assay list?

The assay list covers over 3,000 proteins, spanning immune response, oncology, neurology, cardiometabolic health, and inflammation pathways—all integrated into one platform.

Can I purchase individual Olink Explore 384 panels instead of the full 3072 set?

Yes. Researchers can start with any Olink Explore 384 panel for targeted profiling and later expand to 1536 or 3072 configurations as their project needs grow.

How does the Olink Explore 3072 platform ensure reliable results?

Built-in internal and external controls within every run and the standardized NPX data format provide consistent, reproducible protein quantification across panels and batches.

What types of samples can be used with Olink Explore 384 and 3072 panels?

Explore panels are validated for plasma and serum but can also accommodate CSF, urine, cell culture supernatants, and other research-use-only matrices.

Does Olink Explore 3072 pricing vary by project?

Yes. Olink Explore 3072 price depends on factors like the number of panels used, sample type, and study design. Contact us for a tailored quotation based on your needs.

Are Olink Explore panels suitable for preclinical animal studies?

Yes. Some Explore panels, including mouse-validated options, are compatible with preclinical research and translational projects.

What output data format will I receive?

Results are provided as NPX (Normalized Protein eXpression) values, allowing easy comparison between panels and across studies.

How does Olink reduce off-target effects in its assays?

The dual-antibody PEA system requires both antibodies to bind the same protein before signal amplification, minimizing non-specific signals and ensuring accurate detection.

* For research purposes only, not intended for clinical diagnosis, treatment, or individual health assessments.

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